Half of what people describe as tolerance is a change in the underlying condition, and the two need different answers.

Where does the human data stop and the extrapolation begin? That is the whole thread.

It gets smaller. Not easy, smaller. That distinction kept me going.

Loose evidence and no evidence are different, and people overcorrect in both directions.

Loose evidence and no evidence are different, and people overcorrect in both directions. How long have you been on AOD-9604?

Worth asking what specifically was measured. Pain scores move with mood and function does not.

Reference ranges differ between labs, so comparing two reports is close to meaningless.