Most of the popular protocol is borrowed from a clinical population and applied to healthy people without comment.

Half of what people describe as tolerance is a change in the underlying condition, and the two need different answers.

You have two changes at once here. You cannot attribute anything until one of them moves.

Where does the human data stop and the extrapolation begin? That is the whole thread.

“Registered with” is doing an enormous amount of work in that sentence.

Access to mugs should be on the clinical questionnaire.