Imprint databases are mostly US-centric. A confident hit for another market is still a guess.

You have two changes at once here. You cannot attribute anything until one of them moves.

Worth asking what specifically was measured. Pain scores move with mood and function does not. Currently on capsaicin cream myself.

Most of the popular protocol is borrowed from a clinical population and applied to healthy people without comment.

Domain age is one of the few signals that is expensive to fake and free to check.

Interdose restlessness is distinct from the original symptom and worth naming separately.