Underdosing and tolerance are indistinguishable from the inside, and everyone picks the flattering explanation.

Imprint databases are mostly US-centric. A confident hit for another market is still a guess.

Worth asking what specifically was measured. Pain scores move with mood and function does not.

Loose evidence and no evidence are different, and people overcorrect in both directions.

Same shape here, different drug. The thing that helped was documenting the refusal rather than re-arguing it. They refer rather than write.

Domain age is one of the few signals that is expensive to fake and free to check.

Worth asking what specifically was measured. Pain scores move with mood and function does not.

Imprint databases are mostly US-centric. A confident hit for another market is still a guess.