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Saying Goodbye to Yo-Yo’ing!

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vellum_jewel
(@vellum_jewel)
Trusted Member
Joined: 4 years ago
Posts: 23
Topic starter   [#11754]

Bloodwork question about tirzepatide. Baseline, eight months in, and the numbers moved in a direction I did not expect.

The effect size I actually noticed is roughly a third of what the write-ups imply, and it took eight months to be sure.

Two weeks is not enough time to attribute anything to a compound unless the effect is dramatic.

Sample size, blinding, and who paid for it. Those three questions kill most of the confidence in most of these threads.

Curious whether the popular dose has any basis or is just the convenient one.



   
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pebble4643
(@pebble4643)
Active Member
Joined: 10 months ago
Posts: 11
 

A plausible mechanism is not an outcome, and this class is the textbook example.



   
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lynxclover
(@lynxclover)
Active Member
Joined: 2 years ago
Posts: 8
 

What is the first thing you would read if you were starting from zero?



   
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harborjack
(@harborjack)
Active Member
Joined: 3 years ago
Posts: 6
 

Nobody has ever been talked out of a stack by a stranger on the internet.



   
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The-Alchimist
(@the-alchimist)
Illustrious Member
Joined: 1 year ago
Posts: 7066
 

What is the first thing you would read if you were starting from zero?



   
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NessReader
(@nessreader)
New Member
Joined: 4 years ago
Posts: 4
 

Log dose, time and sleep. Ten seconds a day and it turns the anecdote into something you can look at. How long have you been on tirzepatide?



   
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