Trying to separate three different claims about AOD-9604: that it is the right molecule, that it is the right dose, and that it does something useful.
Two weeks is not enough time to attribute anything to a compound unless the effect is dramatic.
Mechanism is not outcome, and a plausible pathway is the most expensive kind of evidence there is.
Baseline first. Without a baseline the after picture is decoration.
Animal data is much of what exists here and the human stuff is thin and small.
How do you separate the compound effect from the routine around it?
This board overrates bloodwork. A number moving is not the outcome you wanted.
What is the first thing you would read if you were starting from zero?
Underdosing and tolerance are indistinguishable from the inside, and everyone picks the flattering explanation.