I have been running AOD-9604 for a year and the honest summary is that the effect is smaller than the internet suggests and real.
Vivid dreams and mild headache for the first 3 days, then nothing. Textbook for this class, apparently.
Most of the popular protocols are borrowed from clinical populations and applied to healthy people without comment.
Injection site reactions are trivial until they are not, and a fresh needling technique removes half of them.
Willing to accept that my own experience is the weakest evidence in the room.
Sleep, food, or the compound? Yes.
Test one thing at a time. It feels slower and it is the only way to learn anything.
Test one thing at a time. It feels slower and it is the only way to learn anything.
How long before you can reasonably say something is or is not doing anything? Water retention was my main issue with AOD-9604 too.
Sterility is the part people wave through and it is the part that actually bites. How long have you been on AOD-9604?
Log dose, time and sleep. Ten seconds a day and it turns the anecdote into something you can look at.
Three questions kill most of the confidence in a thread like this: sample size, blinding, who paid. Not on AOD-9604 but the pattern is familiar.
What is the first thing you would read if you were starting from zero?
Narrow conclusion, briefly right. Broad conclusion, interestingly wrong. I know which I keep choosing.
A plausible mechanism is not an outcome, and this class is the textbook example. A year in on AOD-9604 and it lines up.
Most of the popular protocol is borrowed from a clinical population and applied to healthy people without comment.