You have two changes at once here. You cannot attribute anything until one of them moves. Currently on doxycycline myself.

Daylight, no flash. Not on a white round tablet but the pattern is familiar.

Test one thing at a time. It feels slower and it is the only way to learn anything.

Three questions kill most of the confidence in a thread like this: sample size, blinding, who paid.

Sleep first. Bad night, bad day, more symptoms. Fix that before changing anything else.