How do you tell the difference between the drug working and just a good week?

Following this because I am in the same place and have no idea what to ask at the appointment. Currently on a concert myself.

Do you contact the customs office or the carrier first?

Sorry, probably obvious, but where do you even start with something blank?

How long before you can reasonably say something is or is not doing anything?

Access to mugs should be on the clinical questionnaire.