Worth asking what specifically was measured. Pain scores move with mood and function does not.

Half of what people describe as tolerance is a change in the underlying condition, and the two need different answers. Five years in on tizanidine and…

Ten percent cuts, of the current dose not the original. That is the arithmetic that keeps it survivable. Not on member ranks but the pattern is famili…

Changing prescriber does not reset anything, and people discover that the hard way.

You have two changes at once here. You cannot attribute anything until one of them moves. Same for me with hydroxyzine, unfortunately.

Half of what people describe as tolerance is a change in the underlying condition, and the two need different answers.

Domain age is one of the few signals that is expensive to fake and free to check.

Worth repeating that this is not medical advice and the answer often depends on who you are.