You have two changes at once here. You cannot attribute anything until one of them moves.

Where does the human data stop and the extrapolation begin? That is the whole thread.

An inconclusive account is useful if it stops the next person mistaking a story for a controlled comparison.

Worth asking what specifically was measured. Pain scores move with mood and function does not.

How do you tell the difference between the drug working and just a good week? Currently on lorazepam myself.