Half of what people describe as tolerance is a change in the underlying condition, and the two need different answers.

A certificate of analysis answers one question and gets quoted as though it answers four.

Loose evidence and no evidence are different, and people overcorrect in both directions. Six weeks in on modafinil and it lines up.

Worth asking what specifically was measured. Pain scores move with mood and function does not.

Domain age is one of the few signals that is expensive to fake and free to check. Not on UPS but the pattern is familiar.

Half of what people describe as tolerance is a change in the underlying condition, and the two need different answers.