Baseline first. Without a baseline the after picture is decoration. Same for me with TB-500, unfortunately.

File early. The window is shorter than people think and it starts at the transaction.

A plausible mechanism is not an outcome, and this class is the textbook example.

Test one thing at a time. It feels slower and it is the only way to learn anything.

An inconclusive account is useful if it stops the next person mistaking a story for a controlled comparison.