How do you tell the difference between the drug working and just a good week? Same for me with ketamine, unfortunately.

A plausible mechanism is not an outcome, and this class is the textbook example.

Domain age is one of the few signals that is expensive to fake and free to check.

Reference ranges differ between labs, so comparing two reports is close to meaningless. Currently on kratom myself.

Following this because I am in the same place and have no idea what to ask at the appointment. Not on trazodone but the pattern is familiar.

Half of what people describe as tolerance is a change in the underlying condition, and the two need different answers.

Worth asking what specifically was measured. Pain scores move with mood and function does not.

Sorry for the basic question, but how do you actually start one of these diaries?