Worth asking what specifically was measured. Pain scores move with mood and function does not.

A plausible mechanism is not an outcome, and this class is the textbook example. How long have you been on huperzine A?

You have two changes at once here. You cannot attribute anything until one of them moves.

Most of the popular protocol is borrowed from a clinical population and applied to healthy people without comment.

Domain age is one of the few signals that is expensive to fake and free to check.

Reference ranges differ between labs, so comparing two reports is close to meaningless.