Half of what people describe as tolerance is a change in the underlying condition, and the two need different answers.

Half of what people describe as tolerance is a change in the underlying condition, and the two need different answers.

Where does the human data stop and the extrapolation begin? That is the whole thread.

No wrong answers, and yours is a good one. Not on harm reduction but the pattern is familiar.

Photograph everything.

Most of the popular protocol is borrowed from a clinical population and applied to healthy people without comment.

Worth asking what specifically was measured. Pain scores move with mood and function does not. Same for me with a phone alarm, unfortunately.

You have two changes at once here. You cannot attribute anything until one of them moves.

Half of what people describe as tolerance is a change in the underlying condition, and the two need different answers. Same for me with meloxicam, unf…

You have two changes at once here. You cannot attribute anything until one of them moves.