Half of what people describe as tolerance is a change in the underlying condition, and the two need different answers.

A plausible mechanism is not an outcome, and this class is the textbook example.

Sterility is the part people wave through and it is the part that actually bites.

Reference ranges differ between labs, so comparing two reports is close to meaningless.

Stupid question: how do you know whether what is in the vial matches the label at all?

Worth asking what specifically was measured. Pain scores move with mood and function does not.