Worth asking what specifically was measured. Pain scores move with mood and function does not.

Half of what people describe as tolerance is a change in the underlying condition, and the two need different answers.

You have two changes at once here. You cannot attribute anything until one of them moves. Currently on a book about a drug myself.

A plausible mechanism is not an outcome, and this class is the textbook example.

Worth asking what specifically was measured. Pain scores move with mood and function does not. Same for me with glycine, unfortunately.

A plausible mechanism is not an outcome, and this class is the textbook example.

Reference ranges differ between labs, so comparing two reports is close to meaningless.

Where does the human data stop and the extrapolation begin? That is the whole thread.