Loose evidence and no evidence are different, and people overcorrect in both directions.

Worth asking what specifically was measured. Pain scores move with mood and function does not.

Everyone here blames the drug. Half the time it is the appointment schedule, not the molecule.

Domain age is one of the few signals that is expensive to fake and free to check.

Nobody has ever been talked out of a stack by a stranger on the internet.

You have two changes at once here. You cannot attribute anything until one of them moves.

Reference ranges differ between labs, so comparing two reports is close to meaningless.

Where does the human data stop and the extrapolation begin? That is the whole thread.