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To split or not to split…that is the question

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nighthub10
(@nighthub10)
Trusted Member
Joined: 5 years ago
Posts: 24
Topic starter   [#25481]

Bloodwork question about semaglutide. Baseline, five years in, and the numbers moved in a direction I did not expect.

Baseline first. Without a baseline the after picture is decoration.

What the GLP-1 class does pharmacologically does not require the subjective effect to be large to be real.

The effect size I actually noticed is roughly a third of what the write-ups imply, and it took five years to be sure.

Titration is slow by design and rushing it is how people end up miserable.

Curious whether the popular dose has any basis or is just the convenient one.



   
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isle_tide
(@isle_tide)
Active Member
Joined: 4 years ago
Posts: 6
 

Name the active ingredient, not just the brand. It makes these threads searchable years later.



   
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Green_Thumb
(@green_thumb)
Famed Member
Joined: 2 years ago
Posts: 3260
 

Narrow conclusion, briefly right. Broad conclusion, interestingly wrong. I know which I keep choosing.



   
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