Trying to separate three different claims about DSIP: that it is the right molecule, that it is the right dose, and that it does something useful.
Sample size, blinding, and who paid for it. Those three questions kill most of the confidence in most of these threads.
Cold storage, light protection, and a date on the vial. Boring, and it removes half the variables.
Animal data is much of what exists here and the human stuff is thin and small.
Happy to be corrected on any of the above.
Reconstitution arithmetic is only half the problem. The other half is what was in the vial.
Underdosing and tolerance are indistinguishable from the inside, and everyone picks the flattering explanation.
Same here.
How long have you been on DSIP?
How long before you can reasonably say something is or is not doing anything?
A plausible mechanism is not an outcome, and this class is the textbook example.
Narrow conclusion.
Narrow conclusion.
Most of what is called evidence here is one person, one vial, one month.