Where does the human data stop and the extrapolation begin? That is the whole thread.
A plausible mechanism is not an outcome, and this class is the textbook example.
Reconstitution arithmetic is only half the problem. The other half is what was in the vial.
Name the active ingredient, not just the brand. It makes these threads searchable years later.
How long before you can reasonably say something is or is not doing anything?
An inconclusive account is useful if it stops the next person mistaking a story for a controlled comparison.
A plausible mechanism is not an outcome, and this class is the textbook example.
Is a baseline blood test really necessary before starting something like this?
Baseline first. Two years in on PT-141 and it lines up.
Three questions kill most of the confidence in a thread like this: sample size, blinding, who paid.
Nobody has ever been talked out of a stack by a stranger on the internet.
What is the first thing you would read if you were starting from zero?
Sleep, food, or the compound? Yes.
Stupid question: how do you know whether what is in the vial matches the label at all?
Loose evidence is not nothing, but a washout either side is the only reason to trust your own take.