Trying to separate three different claims about semaglutide: that it is the right molecule, that it is the right dose, and that it does something useful.
Vivid dreams and mild headache for the first 9 days, then nothing. Textbook for this class, apparently.
If you need three other compounds to notice the first one, you have not tested the first one.
The animal data is stronger than the human data and the human data is not nothing, it is just small.
Titration is slow by design and rushing it is how people end up miserable.
Interested in the methods more than the conclusion.
How long before you can reasonably say something is or is not doing anything? How long have you been on semaglutide?
Read methods.
Loose evidence and no evidence are different, and people overcorrect in both directions.