Meta-level question: how do you evaluate evidence for liraglutide when the human data is thin and most trials are small?
Mechanism is not outcome, and a plausible pathway is the most expensive kind of evidence there is.
What the GLP-1 class does pharmacologically does not require the subjective effect to be large to be real.
The measured outcome and the hoped-for outcome are rarely the same thing in these threads.
What surprised me is how much of the perceived benefit was routine and attention rather than pharmacology.
The interesting question is not whether it works but for whom and at what cost.
This is the kind of post the forum exists for.
My rule, after years of this: if it cannot survive being written down with the numbers attached, it is marketing.
How long before you can reasonably say something is or is not doing anything?
Sterility is the part people wave through and it is the part that actually bites. Currently on liraglutide myself.
Same here.
What is the first thing you would read if you were starting from zero?
Log dose, time and sleep. Ten seconds a day and it turns the anecdote into something you can look at.
Is a baseline blood test really necessary before starting something like this?