Long post, sorry. Victoza (liraglutide): what actually has human evidence behind it, and what is extrapolation from animals?
Tolerance and underdosing look identical from the inside, which is why the answer is usually a blood test and not more forums.
The animal data is stronger than the human data and the human data is not nothing, it is just small.
Titration is slow by design and rushing it is how people end up miserable.
Where does the human data stop and the extrapolation start?
An inconclusive account is useful if it stops the next person mistaking a story for a controlled comparison. Two months in on liraglutide and it lines up.
How long before you can reasonably say something is or is not doing anything?
Loose evidence is not nothing, but a washout either side is the only reason to trust your own take.