Where does the human data stop and the extrapolation begin? That is the whole thread.

If it needs three other compounds to notice, you have not tested the first one.

Test one thing at a time. It feels slower and it is the only way to learn anything.

An inconclusive account is useful if it stops the next person mistaking a story for a controlled comparison.

A plausible mechanism is not an outcome, and this class is the textbook example.

Test one thing at a time. It feels slower and it is the only way to learn anything. Two months in on liraglutide and it lines up.

Sleep, food, or the compound? Yes.

Nobody has ever been talked out of a stack by a stranger on the internet. How long have you been on liraglutide?

Narrow conclusion.

Narrow conclusion.

Stupid question: how do you know whether what is in the vial matches the label at all? How long have you been on liraglutide?

Sterility is the part people wave through and it is the part that actually bites.

Narrow conclusion.

Baseline first.