Trying to separate three different claims about thymosin alpha-1: that it is the right molecule, that it is the right dose, and that it does something useful.
Loose evidence is not the same as no evidence and people overcorrect in both directions.
Sample size, blinding, and who paid for it. Those three questions kill most of the confidence in most of these threads.
Willing to accept that my own experience is the weakest evidence in the room.
Three questions kill most of the confidence in a thread like this: sample size, blinding, who paid. Not on thymosin alpha-1 but the pattern is familiar.
Sterility is the part people wave through and it is the part that actually bites.
An inconclusive account is useful if it stops the next person mistaking a story for a controlled comparison.
Where does the human data stop and the extrapolation begin? That is the whole thread.
Reconstitution arithmetic is only half the problem. The other half is what was in the vial. Currently on thymosin alpha-1 myself.
What is the first thing you would read if you were starting from zero?
How long before you can reasonably say something is or is not doing anything?