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08/05/2021 12:54 am
Long post, sorry. Sulbutiamine: what actually has human evidence behind it, and what is extrapolation from animals?
What the vitamin class does pharmacologically does not require the subjective effect to be large to be real.
Most of the popular protocols are borrowed from clinical populations and applied to healthy people without comment.
Vivid dreams and mild headache for the first 7 days, then nothing. Textbook for this class, apparently.
Two weeks is not enough time to attribute anything to a compound unless the effect is dramatic.
Fat soluble means it accumulates, so the dose ceiling is not theoretical.
Where does the human data stop and the extrapolation start?
08/05/2021 2:16 am
What is the first thing you would read if you were starting from zero?
08/05/2021 2:49 am
Same here.