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The Holy Trinity Stack

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flameyarrow
(@flameyarrow)
Estimable Member
Joined: 3 years ago
Posts: 79
Topic starter   [#30143]

Bloodwork question about rhodiola rosea. Baseline, eight months in, and the numbers moved in a direction I did not expect.

Mechanism is not outcome, and a plausible pathway is the most expensive kind of evidence there is.

Two weeks is not enough time to attribute anything to a compound unless the effect is dramatic.

The evidence is usually a handful of small trials and the effect is modest.

The interesting question is not whether it works but for whom and at what cost.



   
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ridge1993
(@ridge1993)
New Member
Joined: 2 years ago
Posts: 3
 

Loose evidence and no evidence are different, and people overcorrect in both directions.



   
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wrenloom
(@wrenloom)
Active Member
Joined: 3 months ago
Posts: 5
 

Is a baseline blood test really necessary before starting something like this?



   
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hazel8012
(@hazel8012)
New Member
Joined: 5 years ago
Posts: 4
 

How long before you can reasonably say something is or is not doing anything?



   
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sageflame
(@sageflame)
Active Member
Joined: 2 years ago
Posts: 5
 

A plausible mechanism is not an outcome, and this class is the textbook example.



   
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echolatch
(@echolatch)
New Member
Joined: 3 months ago
Posts: 4
 

Narrow conclusion.



   
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huntquill
(@huntquill)
New Member
Joined: 2 years ago
Posts: 3
 

Most of the popular protocol is borrowed from a clinical population and applied to healthy people without comment.



   
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night_cord
(@night_cord)
New Member
Joined: 1 year ago
Posts: 1
 

Is a baseline blood test really necessary before starting something like this?



   
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vellumfield17
(@vellumfield17)
Active Member
Joined: 3 years ago
Posts: 5
 

Most of the popular protocol is borrowed from a clinical population and applied to healthy people without comment.



   
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Green_Thumb
(@green_thumb)
Famed Member
Joined: 2 years ago
Posts: 3260
 

Sleep, food, or the compound? Yes. Same for me with rhodiola rosea, unfortunately.



   
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tor_herb
(@tor_herb)
Active Member
Joined: 7 years ago
Posts: 5
 

Underdosing and tolerance are indistinguishable from the inside, and everyone picks the flattering explanation.



   
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cloversummer
(@cloversummer)
New Member
Joined: 1 year ago
Posts: 3
 

Baseline first.



   
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