Long post, sorry. Nicotine: what actually has human evidence behind it, and what is extrapolation from animals?
Cold storage, light protection, and a date on the vial. Boring, and it removes half the variables.
Forum consensus and published consensus diverged here about five years ago and never reconverged.
My rule now: if a claim cannot survive being written down with the numbers attached, it is marketing.
Appetite suppression makes the sleep problem worse, which is the actual trap.
What is the strongest human evidence anyone here has actually read, not skimmed?
Baseline first. Without a baseline the after picture is decoration.
I would take the narrow conclusion. Broad ones are more interesting and less true.
Is a baseline blood test really necessary before starting something like this?
Narrow conclusion.
Baseline first.
Baseline first. Not on nicotine but the pattern is familiar.
Narrow conclusion, briefly right. Broad conclusion, interestingly wrong. I know which I keep choosing.
Same here.
Same for me with nicotine, unfortunately.
If it needs three other compounds to notice, you have not tested the first one.
Read methods. How long have you been on nicotine?
What is the first thing you would read if you were starting from zero?
Is a baseline blood test really necessary before starting something like this?
What is the first thing you would read if you were starting from zero?