Trying to separate three different claims about adrafinil: that it is the right molecule, that it is the right dose, and that it does something useful.

Sample size, blinding, and who paid for it. Those three questions kill most of the confidence in most of these threads.

Two weeks is not enough time to attribute anything to a compound unless the effect is dramatic.

The animal data is stronger than the human data and the human data is not nothing, it is just small.

Tolerance builds fastest when it is taken for extra hours rather than extra work.

The interesting question is not whether it works but for whom and at what cost.