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I need guidance with an unnecessary redose

25 Posts
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ridgeridge
(@ridgeridge)
Eminent Member
Joined: 2 years ago
Posts: 19
Topic starter   [#40945]

I have been running modafinil for two years and the honest summary is that the effect is smaller than the internet suggests and real.

What the stimulant class does pharmacologically does not require the subjective effect to be large to be real.

Forum consensus and published consensus diverged here about five years ago and never reconverged.

What surprised me is how much of the perceived benefit was routine and attention rather than pharmacology.

Sleep is the limiting factor and it compounds quietly for a fortnight before it is obvious.

Where does the human data stop and the extrapolation start?



   
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nessline19
(@nessline19)
Active Member
Joined: 5 years ago
Posts: 8
 

Sleep, food, or the compound? Yes.



   
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Alex
 Alex
(@alex)
Noble Member
Joined: 2 years ago
Posts: 1841
 

A certificate of analysis answers one question and gets quoted as though it answers four.



   
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flint8154
(@flint8154)
Active Member
Joined: 2 years ago
Posts: 7
 

Nobody has ever been talked out of a stack by a stranger on the internet.



   
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glacier3162
(@glacier3162)
Active Member
Joined: 2 years ago
Posts: 7
 

Three questions kill most of the confidence in a thread like this: sample size, blinding, who paid.



   
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gale2017
(@gale2017)
New Member
Joined: 1 month ago
Posts: 3
 

Most of what is called evidence here is one person, one vial, one month.



   
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jadevale4
(@jadevale4)
Active Member
Joined: 6 years ago
Posts: 5
 

Baseline first.



   
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PineGrain
(@pinegrain)
Active Member
Joined: 3 years ago
Posts: 6
 

If it needs three other compounds to notice, you have not tested the first one.



   
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nesslily91
(@nesslily91)
Active Member
Joined: 4 years ago
Posts: 9
 

Sleep, food, or the compound? Yes. Currently on modafinil myself.



   
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JuliaS
(@julias)
Illustrious Member
Joined: 1 year ago
Posts: 7019
 

Stupid question: how do you know whether what is in the vial matches the label at all?



   
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glinttide
(@glinttide)
Active Member
Joined: 4 years ago
Posts: 8
 

This is the kind of post the forum exists for. Same for me with modafinil, unfortunately.



   
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knolllode90
(@knolllode90)
New Member
Joined: 5 years ago
Posts: 2
 

Sterility is the part people wave through and it is the part that actually bites.



   
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dunehaven91
(@dunehaven91)
New Member
Joined: 5 months ago
Posts: 2
 

A plausible mechanism is not an outcome, and this class is the textbook example.



   
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scaur_jig
(@scaur_jig)
Active Member
Joined: 3 years ago
Posts: 6
 

Loose evidence is not nothing, but a washout either side is the only reason to trust your own take.



   
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wealdsummer47
(@wealdsummer47)
Active Member
Joined: 4 years ago
Posts: 6
 

What is the first thing you would read if you were starting from zero?



   
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