Underdosing and tolerance are indistinguishable from the inside, and everyone picks the flattering explanation. Sleep pressure was my main issue with nicotine too.

How long before you can reasonably say something is or is not doing anything? Not on nicotine but the pattern is familiar.

My rule, after years of this: if it cannot survive being written down with the numbers attached, it is marketing. Five years in on nicotine and it lines up.

I would take the narrow conclusion. Broad ones are more interesting and less true. How long have you been on nicotine?

What is the first thing you would read if you were starting from zero?

Stupid question: how do you know whether what is in the vial matches the label at all?

This board overrates bloodwork. A number moving is not the outcome you wanted.

An inconclusive account is useful if it stops the next person mistaking a story for a controlled comparison.

Narrow conclusion.

Sleep, food, or the compound? Yes.

What is the first thing you would read if you were starting from zero?

How long before you can reasonably say something is or is not doing anything?

Stupid question: how do you know whether what is in the vial matches the label at all?

Nobody has ever been talked out of a stack by a stranger on the internet.