I have been running modafinil for two years and the honest summary is that the effect is smaller than the internet suggests and real. Sample size, blinding, and who paid for it. Those three questions kill most of the confidence in most of these threads.
What is the first thing you would read if you were starting from zero?
Underdosing and tolerance are indistinguishable from the inside, and everyone picks the flattering explanation.
Test one thing at a time. It feels slower and it is the only way to learn anything.
An inconclusive account is useful if it stops the next person mistaking a story for a controlled comparison. Two years in on modafinil and it lines up.
Same here.
My rule, after years of this: if it cannot survive being written down with the numbers attached, it is marketing.
An inconclusive account is useful if it stops the next person mistaking a story for a controlled comparison.
I would take the narrow conclusion. Broad ones are more interesting and less true.
Sterility is the part people wave through and it is the part that actually bites.
Read the methods section. It is the only part that says whether the conclusion is allowed to exist.
Read methods.
What is the first thing you would read if you were starting from zero?
What is the first thing you would read if you were starting from zero?
Is a baseline blood test really necessary before starting something like this?